DETOXIFICATION THERAPIES1. Dimercapto-1-propane sulfonic acid (DMPS)
- DMPS is used mostly for Mercury toxicity, but it can also helps with Arsenic, Lead, Cadmium, etc.
- Human studies with the chelating agents, DMPS and DMSA
- Urinary mercury after administration of 2,3-dimercaptopropane-1-sulfonic acid: correlation with dental amalgam score
- Chelation: Harnessing and Enhancing Heavy Metal Detoxification—A Review2. Ethylenediamine Tetraacetic Acid (EDTA)
EDTA chelation is FDA approved for treatment of heavy metal toxicity such as Lead, Cadmium, etc.
- Chelation: Harnessing and Enhancing Heavy Metal Detoxification—A Review
- EDTA chelation therapy in the treatment of toxic metals exposure
2.1. EDTA for heavy metal chelation
Global pollution is the number cause of morbidity and mortality on the planet
- Loss of life expectancy from air pollution compared to other risk factors: a worldwide perspective
- Global pollution is the world's biggest killer and a threat to survival of mankind, study finds
Heavy metal toxicity is a major component of pollution
- Heavy Metals Toxicity and the Environment
2.2. EDTA for cardiovascular diseases
EDTA has not been approved by the FDA for cardiovascular diseases.
However, the TACT trial shows that there is a reduction in cardiovascular events, especially in diabetes patients
- Effect of Disodium EDTA Chelation Regimen on Cardiovascular Events in Patients With Previous Myocardial InfarctionThe TACT Randomized Trial
The second TACT2 trial is now in progress.
EDTA and cancer
EDTA is not approved for cancer but may help to reduce mortality from cancer
- Ninety Percent Reduction in Cancer Mortality after Chelation Therapy With EDTA
2.4. EDTA and Hypertension
- Improvement of Essential Hypertension After EDTA Intravenous Infusion Treatment
3. Diethylenetriaminepentaacetic acid (DTPA)
- DTPA is used mostly for Gadolinium toxicity.
- Intravenous Calcium-/Zinc-Diethylene Triamine Penta-Acetic Acid in Patients With Presumed Gadolinium Deposition Disease: A Preliminary Report on 25 Patients4. Glutathione
- Intravenous Glutathione may help with detoxification.SUPPORTIVE THERAPIESLow-Dose Vitamin C/Myers Cocktail
- Intravenous vitamin C < 15 g and B-complex and minerals may help to improve hydration, energy and nutritional status.
High-Dose Vitamin C
- patients need to be tested for G6PD before treatment
- Intravenous vitamin C > 15 g up to 100 mg may help to support quality of life in cancer patients
- Intravenous High-Dose Vitamin C in Cancer Therapy by National Cancer Institute
- IVC ProtocolEssential Phospholipids (EPL)
Intravenous Phosphatidylcholine may help with certain conditionsAlpha Lipoic Acid (ALA)
Intravenous ALA may help with certain type of nerve problem
- Alpha Lipoic Acid for Symptomatic Peripheral Neuropathy in Patients with Diabetes: A Meta-Analysis of Randomized Controlled Trials