COVID-19

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COVID-19

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Updated 7/5/2020 
SARS-CoV-2 / COVID-19

COVID-19 Symptoms

 

Covid Testing Time Course
SARS-CoV-2  Name given by International Virus Classification Commission
COVID-19      Name given by World Health Organization
 
3CLpro          3C-like main protease (3CLpro)
ACE2             Angiotensin-converting enzyme 2
EGCG            Epigallocatechin gallate
EMFs/EMR   Electromagnetic fields/Electromagnetic radiation
H2O2            Hydrogen peroxide
M&M             Morbidity and Mortality
N                  Nucleocapsid
PLpro            Papain-like proteinase
RdRp             RNA-dependent RNA polymerase
                 Spike protein
           

I. STRESS REDUCTION
Latest study shows that 50% of Americans are fearful of the current situation.

The reason for this fear because it is fear of the unknown future. One needs to understand the future of this situation in order to maintain a proper attitude, which is the most important factor in health because stress decreases the immune system.

All predictive models are based on data from M&M data. Different models will give different predictions. These models are not accurate because they do not take account for other factors: Environmental factors and Human behaviors.

 

ENVIRONMENT     *      HUMANS                     =>     M&M data

Virus                              Health consciousness         Infection rate with Reproduction number R naught, Death rate

Air pollution
EMFs/EMR                          


I.1. COVID-19

I.1.1. The nature of viruses
Debates exist whether viruses are alive or not
- Are viruses alive?
Presently, most virologists and biologists classify them as non-living

A virus is a microscopic particle that can infect the cells of a biological organism
Therefore, viruses are not included in the Tree of Life
- The Tree of Life


The answer is that viruses are partial non-living partial living. They border between non-life and life. They have these characteristics that make them alive:

1. They have a survival consciousness: they mutate to survive. Non-living things do not have a survival consciousness and do not mutate to survive because they don't respond to stimuli
- Non-living things
2. They can self-assemble. Non-living things can not self-assemble
- Physical virology: From virus self-assembly to particle mechanics

3. They have a life cycle. Non-living things do not have life cycles
- The Viral Life Cycle

4. They are dependent on non-living things to survive: they are dependent on a medium to survive, e.g., they infect a cell and can be cultured in a lab. Non-living things do not infect cells and can not be cultured in a lab.

 

This distinction is important because since viruses are dependent on non-livings to survive, the non-living medium can be taken away to decrease the survival of viruses. An analogy is flies and trash. Flies can be killed but as long as the trash is present, the flies will come back. Taking care of the trash will help to reduce the flies.

 

Interactions between infections and toxins

- Bringing the Bugs Back In: Environmental Health Research Model Combines Toxicology and Infectious Disease.

- A niche for infectious disease in environmental health: rethinking the toxicological paradigm.

Interactions between infections and Ionizing radiation

Treatment of infections after exposure to ionizing radiation.

Interaction between infections and Non-ionizing radiation EMFs/EMR

- Exposure to a 50 Hz electromagnetic field induces activation of the Epstein-Barr virus genome in latently infected human lymphoid cells.
- Mold Produces 600 Times More Bio-Toxins with EMF.


Therefore, controlling the environment will hep to control the infections.


I.1.2. Coronavirus
I.1.2.1. Generally, Coronavirus is a seasonal virus, beginning in winter and tapering off around end of April and going out in summer

What are the seasonal patterns of rhinoviral, coronaviral, enteroviral, and adenoviral upper respiratory tract infections (URIs)?
- Epidemiology and clinical presentations of the four human coronaviruses 229E, HKU1, NL63, and OC43 detected over 3 years using a novel multiplex real-time PCR method


I.1.2.2. There are treatments that are potentially effective, such as
I.1.2.2.1. Hydroxychloroquine
- WHO Launches Global Megatrial of the Four Most Promising Coronavirus Treatments

IHU Méditerranée Infection
- Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial
However, the WHO has halted trial of Hydroxychloroquine based on a study that claims that this treatment is not effective and has side effects
- Hydroxychloroquine or chloroquine with or without a macrolide for treatment of COVID-19: a multinational registry analysis

This study has caused more than 180 scientists around the world to sign a petition that raises concerns about inconsistent data
- Scientists Expose Lancet Study Critical Of HCQ COVID-19 Treatment
- Concerns regarding the statistical analysis and data integrity
especially that Chloroquine is on the WHO Model List of Essential Medicines
- World Health Organization Model List of Essential Medicines 2019
And reviewing the data, the WHO resumes the trial
- WHO resumes study of hydroxychloroquine for COVD-19 after safety review
And the study was retracted
- Retraction-Hydroxychloroquine or chloroquine with or without a macrolide for treatment of COVID-19: a multinational registry analysis

It is possible that the efficacy depends on the early use in outpatient settings

- Prestigious Medical Journal Endorses Hydroxychloroquine For COVD-19
Early Out patient Treatment of Symptomatic, High-Risk Covid-19 Patients that Should be Ramped-Up Immediately as Key to the Pandemic Crisis

A larger observational study shows that its use is associated with a reduction in mortality
- Among hospitalized pateints, use of Hydroxychloroquine alone and in combination with Azithromycin was associated with a significant reduction in-hospital compared to not receving Hydroxychloroquine

I.1.2.2.2. Remdesivir

Coronavirus (COVID-19) Update: FDA Issues Emergency Use Authorization for Potential COVID-19 Treatment

I.1.2.2.3. Ivermectin

Breakthrough Drug: Ivermectin Shows 'Asounding' Results Against Coronavirus

I.1.2.3. As doctors understand the disease process better, they will be able to treat the disease better
Initially, hospitalists followed the protocols by the Chinese and the Italians by putting the patients with low Oxygen on ventilators early. Eventually, they found out that certain patients have higher mortality if put on ventilators prematurely
- Doctors Suspect Mystery COVID-19 Lung Problems, Plea for New Approach
- Mortality rate of COVID-19 patients on ventilators
The Italians now think that COVID-19 does not lead to a typical lung syndrome, at least in some patients
- Covid-19 Does Not Lead to a "Typical Acute Respiratory Distress Syndrome"
So they propose different approaches to patients with different clinical features
1. Patients with typical lung failure problems should be put on ventilators
2. Patients without typical lung failure problems should not be put on ventilators but be given Oxygen support
- COVID-pneumonia: different respiratory treatment for different phenotypes?

Changing the position of patients with hypoxemia can help to avoid intubation in some patients
- Use of Prone Positioning in Nonintubated Patients With COVID-19 and Hypoxemic Acute Respiratory Failure

There is evidence that the virus infects blood vessels causing blood clots
- Endothelial cell infection and endotheliitis in COVID-19


With all the above understandings, there should be better treatments and the mortality rate should decrease around end of May.


I.2. Air pollution

As explained later, in summer, air pollution will decrease, so respiratory illnesses will also decrease.

 
I.3. Health Consciousness

People will be more health conscious and will take better care of themselves with better hygiene, diet, supplements and exercise. Therefore, people will be healthier to protect themselves against the virus.

 

With the above factors, death rates should go down soon and mortality should be lower than initially predicted. Understand this whole big picture should clarify the future of this situation to relieve fear and stress.

For stress
Fermented Ginseng: 100 mg x 2-4 a day on empty stomach

- Effects of ginseng on stress-related depression, anxiety, and the hypothalamic–pituitary–adrenal axis
 

II. AIR

II.1. Outdoor Air Quality
Air pollution is worse in winter and better in summer due to a phenomenon in nature called “Temperature Inversion”

- Why Is Air Pollution Worse During Winter?
  

There is a relationship between toxins and infections, very much like trash and flies. Since air pollution is worse in winter, respiratory infections are also worse in winter

- Linking pollution and infectious disease
- Is there a link between pollutant exposure and emerging infectious disease?

- Air pollution and respiratory viral infection

A Prospective Study of the Impact of Air Pollution on Respiratory Symptoms and Infections in Infants

- Seasonality of Primary Care Utilization for Respiratory Diseases in Ontario: A time-Series Analysis

There are now studies that show links between air pollution and COVID-19 morbidity and mortality rates
Air pollution linked with higher OCVID-19 dealth rates
-
 Two mechanisms for accerelated diffusion of COVID-19 outbreaks in regions with high intensity of population and polluting industrialization: the air pollution-to-human and human-to-human tranmission dynamics

- The Potential role of Particulate Matter in the spreading of COVID-19 in Northern Italy: First Evidence-based Research Hypotheses
- SARS-Co-2 RNA Found on Particulate Matter of Bergamo in Northern Italy: First Preliminary Evidence
Regional air pollution persistence links to COVID-19 infeciton zoning

Therefore, when air pollution becomes better in summer, COVID-19 infections will decrease.

II.2. Indoor Air Quality

This air purifier puts out H2O2 and other similar molecules to kill infections

- AIR & SURFACE PRO The Most Powerful Surface and Air Cleaning Technology Ever Discovered


H2O2 inactivates Coronavirus 229E

- Virus Inactivation by Hydrogen Peroxide


It kills 99.99% of viruses and bacteria and fungus tested

Scientific Proof: Results based on laboratory testing

I.3. EMFs/EMR

On one hand, currently, there is no definitive proof that EMFs/EMR, such as 5G, causes the pandemic.
On the other hand,

I.3.1. There is an positive correlation between 5G and morbidity/mortality in the US, i.e., in states with 5G, COVID-19 cases per million are 95% higher and deaths per million are 126% higher than in states wihtout 5G
Is there an association between covid-19 cases/deaths and 5G in the United States?

I.3.2. There is evidence that EMFs/EMR can cause immune system problem
- Effects of electromagnetic fields on the immune systems of occupationally exposed humans and mice
- Disturbance of the immune system by electromagnetic fields-A potentially underlying cause for cellular damage and tissue repair reduction which could lead to disease and impairment
- Effect of electromagnetic fields on several CD markers and transcription and expression of CD4


III. WATER AND HEAT

The virus has a lipid coating, and heat melts lipid, so heat can inactivate and kill the virus.

III.1. Temperature > 132.8 F x 90 min, > 152.6 F x 60 min, > 176 F x 30 min kills SARS, so drink hot water/tea throughout the day without causing throat burn

- Stability OF SARS Coronavirus in Human Specimens and Enviroment and its Sensitivity to Heating and UV Irradiation


Add salt/essential oils to hot water and gargle 2 – 3 x a day. Salt may kill the virus in the throat. There is no evidence that salt it is effective for COVID-19, but it is safe, unless it makes the sore throat worse

- Universal and Reusable Virus Deactivation System for Respiratory Protection


Inhale hot water/essential oils to kill virus in the nose/sinus.


III.2. Fever
Fever is a natural response and should not be suppressed
- Fever: suppress or let it ride?
- The Case for Letting Fevers Run Their Course

Temperature >100.4 F inactivates SARS virus

- The Effects of Temperature and Relative Humidity on the Viability of the SARS Coronavirus


Centuries of experience from traditional cultures show that home sauna therapy, such as Vietnamese style "Xong", often gives improvement the next day.
Vietnamese style “Xong”:

- boil a large pot of water

- add fresh lemongrass or its essential oils, or any essential oils, spices, herbs, etc.

- place the pot on the floor

- take off clothes and sit next to the pot

- cover the body and pot with a blanket

- sweat as much as possible until the water is no longer hot

- clean sweat off

- can repeat as needed

- be careful if there are blood pressure or hydration problems

 

IV. FOODS
This is the time to eat natural organic foods and avoid processed foods like sweets which lower the immune system.

IV.1. Eat foods high in Zinc
Zinc: Fact Sheet for Health Professionals


IV.1.1. Zinc is important because it inhibits the viral enzyme RdRp used for replication inside the cell
- Zn2+ Inhibits Coronavirus and Arterivirus RNA Polymerase Activity In Vitro and Zinc Ionophores Block the Replication of These Viruses in Cell Culture

All Coronaviruses use this enzyme to replicate
- Structure of the RNA-dependent RNA polymerase from COVID-19 virus

Remdesivir, one of the drugs being tested in trials by WHO, works by inhibiting this enzyme
-The antiviral compound remdesivir potently inhibits RNA-dependent RNA polymerase from Middle East respiratory syndrome coronavirus

One of the symptoms of COVD-19 is loss of smell and taste
Loss of smell and taste is a classic symptom of Zinc deficiency
- The Role of Zinc in Antiviral Immunity
- Modulating the Immune Response Oral Zinc supplementation: A single apporach for multiple disease

WHO estimates the global prevalence of Zinc deficiency as 31% with the range from 4-73% across subregions, based on the work of the International Zinc Nutrition Consultative Group (IZiNCG)
- Zinc deficiency
The IZiNCG uses the estimate based on the work of US NHANES II study

Optimal range, however, should be higher, with a lower cutoff serum Zinc level of 84 ug/dL

Therefore, global prevalence of Zinc deficiency is most likely higher than the WHO estimate 31%. Using the optimal lower cut off serum Zinc 84 ug/dL, personal experience has shown that prevalence of Zinc deficiency in the Los Angeles population is about 80%.

IV.2. Decrease grains that have Gluten which decreases Zinc absorption
The concentration of serum zinc in celiac patients compared to healthy subjects in Tehran
- Serum zinc in small children with coeliac disease

IV.3. Be aware that Acid Blockers  reduce Zinc absorption.

- Malabsorption-Related Issues Associated with Inhibitor Usage
- Proton Pump Inhibitors Interfere with ZInc absorption and Zinc body stores

IV.4. Environmental toxins can cause Zinc deficiency
In general, in the Periodic table, in the same column, heavier elements tend to displace lighter elements.
Zinc is in           Group 12, Period 4
Cadmium is in  Group 12, Period 5
Mercury is in    Group 12, Period 6
- Periodic table
Therefore,
Excess Cadmium, which is commonly found, can cause Zinc deficiency
Interactions between cadmium and zinc in the organism
Excess Mercury toxicity, which is commonly found, can cause Zinc deficiency
Mercury exposure, nutritional deficiencies and metabolic disruptions may affect learning in children

IV.5. Eat foods high in bioflavonoids such as vegetables and fruits, especially citrus fruits including the rinds but not fruit juices. Certain bioflavonoids inhibit various process of viral infection cycle
- Bolstering Your Defenses Against COVID-19: An “Epigenetic” Diet
- List of phytochemicals in food

USDA Database for the Flavonoid Content of Selected Foods

IV.6. Eat foods to control hyperglycemia, because hyperglycemia, regardless of the status of diabetes, increases morbidity and mortality of COVID-19 patients, most likely because hyperglycemia increases glycosylation of the virus and the ACE2 receptor

- Hyperglycemia, Hydroxychloroquine, and the COVID-19 Epidemic

V. SUPPLEMENTS

Despite no information about supplements for COVID-19, we can base our protocol on information from studies of other Coronaviruses, computer models, lab studies, animal studies and preliminary human studies.
V.1. For blocking viral entry into the cell

S is a virus protein that bind to ACE2 receptor on human cell. Human cell has the enzyme Furin which cleaves the S into subunits S1 and S2. S1 then binds to ACE2 receptor to enter the cell.
- The spike glycoprotein of the new coronavirus 2019-nCoV contains a furin-like cleavage site absent in CoV of the same clade
- Drug targets for corona virus: A systematic review
- The proximal origin of SARS-CoV-2

- Why does SARS-CoV-2 spread so easily?

V.1.a. Furin inhibitor

Luteolin: 100 mg x 2-4 a day on empty stomach
- Luteolin restricts dengue virus replication through inhibition of the proprotein convertase furin
 
There are other bioflavonoids that are furin inhibitors: Chrysin, Naringin, Rutin, etc.
- Chemical structure and properties of low-molecular furin inhibitors


V.1.b. ACE2 receptor inhibitor

Hesperidin: 500 mg x 2-4 a day on empty stomach

- Analysis of Therapeutic Targets for SARS-CoV-2 and Discovery of Potential Drugs by Computational Methods
 

Polygonum multiflorum which contains Emodin: 500 mg x 2-4 a day empty stomach
- Emodin Blocks the SARS Coronavirus Spike Protein and Angiotensin-Converting Enzyme 2 Interaction

 

Lactoferrin: 300 mg x 2-4 a day on empty stomach

Inhibition of SARS Pseudovirus Cell Entry by Lactoferrin Binding to Heparan Sulfate Proteoglycans
It activates intestinal production of Interferon-Lambda which renders lung cells resistant to the virus

- Effects of lactoferrin on the production of interferon-λ by the human intestinal epithelial cell line HT-29
- Lambda interferon renders epithelial cells of the respiratory and gastrointestinal tracts resistant to viral infections

There are other bioflavonoids that are ACE2 receptor inhibitors: Chlorogenic acid, Daidzein, Luteolin, Quercetin, Rosmarinic acid, Rutin, Ursolic acid, etc.

- Discovery of Anti-2019-nCoV Agents from 38 Chinese Patent Drugs toward Respiratory Diseases via Docking Screening

V.2. For virus inside the cell
The following enzymes are used for replication, thus are targets for inhibition

- RdPp

- PLpro

- 3CLpro

- Helicase

- N

 

V.2.a. RdRp inhibitor

Zinc (elemental) blocks this enzyme: 20 – 30 mg x 1-4 a day with food
- Zn(2+) inhibits coronavirus and arterivirus RNA polymerase activity in vitro and zinc ionophores block the replication of these viruses in cell culture

- Zinc Iodide in combination with Dimethyl Sulfoxide for treatment of SARS-CoV-2 and other Viral Infections 

Zinc ionophore transports Zinc into the cell. Chloroquine has many antiviral mechanisms, and one mechanism is that it is a Zinc ionophore (clinically, use Hydroxychloroquine and not Chloroquine)

Chloroquine Is a Zinc Ionophore

 

Quercetin, EGCG are Zinc ionophores

- Zinc Ionophore Activity of Quercetin and Epigallocatechin-Gallate: from Hepa 1-6 cells to a Liposome Model
 

Quercetin: 1000 mg x 2-4 a day on empty stomach

EGCG from Green tea: 500 mg x 2-4 a day with food
 

Bee Propolis: 3000 mg x 2-4 a day on empty stomach

- Effects of propolis flavonoids on virus infectivity and replication
 

Theaflavin from Black tea: 500 mg x 2-4 with food
- The potential chemical structure of anti-SARS-CoV-2 RNA-dependent RNA polymerase


V.2.b. PLpro inhibitor

EGCG
- Analysis of therapeutic targets for SARS-CoV-2 and discovery of potential drugs by computational methods


V.2.c. 3CLpro inhibitor

Hesperidin
Quercetin
EGCG
- Analysis of therapeutic targets for SARS-CoV-2 and discovery of potential drugs by computational methods

- Flavonoid-mediated inhibition of SARS coronavirus 3C-like protease expressed in Pichia pastoris

V.2.d. Helicase inhibitor

Hesperidin
- Analysis of therapeutic targets for SARS-CoV-2 and discovery of potential drugs by computational methods

V.2.e. N inhibitor

Resveratrol: 250 mg x 2-4 a day with food

Effective inhibition of MERS-CoV infection by Resveratrol


V.3. For virus in the general system

Oregacillin (Oregacyn): 1 x 2-4 a day on empty stomach

- Final Report: VIRUCIDAL EFFECTIVENESS TEST Coronavirus

V.4. For general Immune system

Even though there are no proofs that certain vitamins and minerals help directly with COVID-19, there are evidences that they may help indirectly by enhancing immune system
Enhancing immunity in viral infections, with special emphasis on COVID-19: A review


V.4.1. Vitamin C with bioflavonoids: 500 mg x 2-4 a day with food

 Vitamin C and SARS Coronavirus 


V.4.2. Selenium: 200 ug a day with food
Association between regional selenium status and reported outcome of COVID-19 cases in China

V.4.3. Vitamin D3: 5,000 - 20,000 IU a day with food to keep serum 25-hydroxyvitamin D > 60 ng/mL
Evidence that Vitamin D Supplementation Could Reduce Risk of Influenza and COVID-19 Infections and Deaths
Optimisation of Vitamin D Status for Enhanced Immuno-protection Against Covid-19

V.4.4. Alkalinization
There is no evidence that Alkalinization is effective for COVID-19, but it can be helpful for general infections
- Virucidal efficacy of sodium bicarbonate on a food contact surface against feline calicivirus, a norovirus surrogate
Effect of sodium bicarbonate 8.4% on respiratory tract pathogens
Effect of adding inhalation of sodium bicarbonate 8.4% to the usual treatment on smear-positive pulmonary tuberculosis: a prospective controlled study

Sodium bicarb shifts macrophage M1 (inflammatory) to M2 (regulatory) phenotypes
Oral NaHCO3 activates a splenic anti-inflammatory pathway; evidence cholinergic signals are transmitted via mesothelial cells

However, using Baking soda is complicated because urine pH needs to be monitored and there are relative contraindications such as blood pressure and water retention problems, so it is best supervised by a doctor knowledgeable in pH interpretation.

VI. INTRAVENOUS TREATMENTS
Intravenous vitamin C at least 15 g

- Shanghai Government Officially Recommends Vitamin C for COVID-19

VII. SUMMARY

1. Manage stress
2. Purify air
3. Minimize EMFs/EMR
4. Drink hot water/teas
5. Eat natural organic foods high in Zinc and bioflavonoids
6. Take supplements
7. Hot sauna

ENVIRONMENT

BODY

Infections

Pollution

Radiation

Stress

Nose

Throat

Virus - cell interface

Virus
in cell

Immune

system

Purify air

Minimize EMFs/EMR

 

Manage

Inhale hot vapor

Drink hot water/teas

Use Essential oil

Use Zinc spray

Flavonoids foods

Propolis

Luteolin

Lactoferrin

Hesperidin

Oregacillin 

Zinc foods
Zinc

Propolis

Lactoferrin

Hesperidin

EGCG

Resveratrol

Citrus foods

Vit C
Vit D3
Selenium

Sauna/“Xong”

 


PERSONAL RECOMMENDATIONS FOR SUPPLEMENTS
The best medicines of the people, by the people, for the people, have the following criteria:
1. Accessibility
2. Affordability
3. Practicality

Personal experience has led to this recommendation for a protocol that satisfy the above criteria: Propolis and Zinc. Other supplements can be added.

1. Propolis contains many ingredients mentioned above to
A. inhibit viral entry into the cell
B. act as Zinc ionophore to transport Zinc into the cell
C. inhibit viral replication inside the cell

- Chlorogenic acid inhibits ACE2
- Chrysin inhibits Furin
- Daidzen inhibits ACE2
- Luteolin inhibits Furin, ACE2
- Hesperidin inhibits ACE2, 3CLpro, Helicase
- Naringin inhibits Furin
- Quercetin inhibits ACE2, acts as Zinc ionophore, inhibits 3CLpro
- Resveratrol inhibits N replication
- Rosmarinic acid inhibits ACE2
- Rutin inhibits Furin, ACE2
- Antioxidant Potential of Propolis, Bee Pollen, and Royal Jelly: Possible Medical Application
-
Brazilian Red Propolis—Chemical Composition and Botanical Origin
-
Identification of Resveratrol as Bioactive Compound of Propolis from Western Romania and Characterization of Phenolic Profile and Antioxidant Activity of Ethanolic Extracts
-
Propolis and some of its constituents down-regulate DNA synthesis and inflammatory cytokine production but induce TGF-beta1 production of human immune cells
Revisiting Greek Propolis: Chromatographic Analysis and Antioxidant Activity Study

- Composition and functional properties of Propolis (bee glue): A Review

2. Zinc inhibits RdRp replication.

Zinc can be used alone if in nanoparticle form
- Zinc Iodide in combination with Dimethyl Sulfoxide for treatment of SARS-CoV-2 and other viral infections
This Nano Zinc Iodide supplement is being tested currently at a hospital. The prelimary trial shows that it is effective within 24 hours.

This protocol is similar to the protocol of Hydroxychloroquine+/-Azithromycin and Zinc. Many researchers and scientists think that this protocol needs to be tested in clinical trials, but they are not clinicians who treat patients. Clinicians have used this protocol with success
IHU Méditerranée Infection
- One America News: NY Doctor Finds Success Treating COVID-19 Patients With Hydroxychloroquine Cocktail
- LA doctor seeing success with hydroxychloroquine to treat COVID-19

Likewise, personal experiences of various doctors using the protocol of Propolis and Zinc see improvement within 24 hours.
This protocol is be used for mild cases at home. Moderate to severe cases need to be treated at the hospitals.

VIII. CASE STUDIES
Case 1 - by Huy Hoang, MD
55 year old healthy female

4/24: cough and sore throat
4/26: PCR +
5/4:   Propolis 1500 mg 2 x 4 a day + Nano Zinc Iodide 5 mL x 3 a day
5/5:   felt better
          Propolis helped with the cough/mucus
5/7:   all symptoms resolved
5/9:   stopped supplements
5/15: PCR -

Case 2 - by Huy Hoang, MD
26 year old healthy male
5/19: sore throat, diarrhea, fever, loss of taste and smell, body aches and chills
5/22: PCR +
5/27: Nano Zinc Iodide 5mL x 2 a day
5/29: felt better
6/1:   all symptoms resolved
6/4:   PCR -

Case 3 - wife of patient in Case 2 by Huy Hoang, MD
26 year old healthy female
6/3:   fever, loss of taste
6/3:   Propolis 3000 mg x 4 a day empty stomach
          Nano Zinc Iodide 5 ml x 2 a day
6/5:   felt better, fever resolved
6/10: PCR +
6/15: loss of taste resolved
6/19: PCR -
Note: the PCR + on 6/10 was probably dead virus

Case 4 - from a Russian hospital, contributed by Ba Hoang, MD, PhD
ZnDM-COVID-O: oral Nano Zinc Iodide DMSO

Day 1: a 76 year-old male with a medical history of prostate cancer with bone, lung and lymphatic metastasis and 51 years of moderate smoking presented to the clinic with fever of 38.7 °C, muscle and body aches, severe dry cough with difficult breathing, sore throat, abdominal pain and extreme fatigue. The patient’s symptoms were developed and aggravated for 6 days period when he had been tested positive for COVID-19 by RT-PCR of nasopharyngeal swab material. The patient had an X-ray examination and the results showed bilateral lower lobe pneumonia. The patient’s SpO2 level was 78% and pulse rate was 120 per minute.
The patient started
treatment with oxygenation therapy via mask 6 liters per minute, bronchodilator inhalation, paracetamol 1000 mg IV and 10 ml of ZnDM-COVID-O mixing with 200 ml of water.
In 2
hours after the initial treatment, the patient’s condition improved remarkably. His muscle and body aches drastically reduced, his SpO2 increased to 92% with oxygen therapy of 3 liters per minute, his pulse rate was 98 per minute and his fever dropped to 36.7 °C. The patient was administered 10 ml of ZnDM-COVID-O with 200 ml of water in 6 hours from the initial treatment without other therapeutic drugs.
After 10 hours from the beginning of the treatment,
the patient’s pain, breathing pattern, energy were all improved, his temperature remained normal, his SpO2 was 94% with no needs of oxygen therapy and his dry cough reduced more than 70%.
He slept 3 hours for the first time in 3 days and he was able to eat and drink twice as much compared to the day before. The patient had been treated with 10 ml of ZnDM-COVID-O every 8 hours for the next 48 hours.
He continued clinically improve in all of his complaints and
symptoms.
Day 3: the patient’s temperature was normal, he
slept 5 hours at night, his appetite, energy and shortness of breath improved more than 70%, he had no more dry cough and even no body and chest pains that were related to the prostate cancer experienced before the COVID-19 diagnosis. His SpO2 was 95% and pulse rate was 86 per minute.
The patient continued to take ZnDM-COVID-O 10 ml 3 times daily for 7 days more.
Day 10:
all his symptoms related to COVID-19 had resolved and his general health condition remarkably improved.
Day 11: The X-ray examination showed
that the bilateral lobe pneumonia resolved completely.
The patient continued to take ZnDM-
COVID-O 5 ml 3 times daily for 5 more days.
Day 14:The COVID-19 test by RT-PCR of nasopharyngeal swabs materials negative for SARS-CoV-2 RNA.
Day 16: RT-PCR negative for SARS-CoV-2 RNA and discharged from the clinic.

Case 5 - from a Russian hospital, contributed by Ba Hoang, MD, PhD
ZnDM-COVID-SN: Nano Zinc Iodide DMSO Spray and Nebulization
Day 1: a 54 year-old male with a medical history of Crohn’s diseases and asthma presented to the clinic
with high fever of 39.5°C, severe shortness of breath, dry cough, chest congestion and pain, diarrhea with blood, extreme fatigue, body aches and anosmia. A chest X-ray examination confirmed bilateral pneumonia with hazy opacities. The patient was diagnosed with suspected COVID-19 due to his close contact with relatives who had confirmed COVID-19 infections 7 days earlier. The patient SpO2 was 75% with 5 liters of oxygen therapy per minute via mask and his pulse rate was 110 per minute.
The patient was treated with ZnDM-COVID-O with the doses of 5 ml with 200 ml of water every 6 hours and 5 ml of ZnDM-COVID-SN via nebulization every 8 hours for 72 hours, Paracetamol 1000 mg IV and bronchodilator inhalation.
In 4 hours after the initial treatment the
patient’s symptoms had improved with remarkable reduction in dry cough, shortness of breath,
fatigue and chest pain. The SpO2 reading was 92% with oxygen therapy of 3 liters per minute and pulse rate dropped to 92 per minute. His temperature was 37.2 °C.
Day 3:
all of the patient’s symptoms related to his current disease were improved allowing him to breath without a significant shortness of breath and chest pain without oxygen therapy and bronchodilators treatment. His temperature was in normal range, SpO2 was 96% and pulse rate was 85 per minute.
The patient had continued
treatment with ZnDM-COVID-O 5 ml every 6 hours without nebulization and oxygen treatment for 12 days.
Day 4: blood diarrhea resolved completely. RT-PCT testing of nasopharyngeal swab material taken on admission confirmed COVID-diagnosis.
Day 6: no symptoms related to his current disease and respiratory functional
limitation.
Day 14:
RT-PCR testing of nasopharyngeal swab materials negative for SARS-CoV-2 RNA.
Day 15: chest X-Ray examination revealed no sign of pneumonia.

IX. OTHER VIRUSES

In case it is a cold/flu and not COVID-19, add Colostrum and Sambucus because personal experience has shown that this combination works close to 100% for the cold/flu, better than vitamin C, Chinese herbs and Western herbs.

Colostrum: 3000 mg x 2-4 a day on empty stomach
Prevention of Influenza Episodes With Colostrum Compared With Vaccination in Healthy and High-Risk Cardiovascular Subjects: The Epidemiologic Study in San Valentino

Sambucus-D: 1 Tablespoon x 4 a day on empty stomach

Randomized Study of the Efficacy and Safety of Oral Elderberry Extract in the Treatment of Influenza A and B Virus Infections
- Inhibition of several strains of influenza virus in vitro and reductino of symptoms by an elderberry extract (Sambucus nigra L.) during an outbreak of influenza B Panama

- Black elderberry (Sambucus nigra) supplementation effectively treats upper respiratory symptoms: A meta-analysis of randomized, controlled clinical trials


At the office, we have the air purifiers that release H2O2 into the air in the reception and IV areas.

Practice your hygiene, have no fear and move on with your life.

Huy Hoang, M.D.

 

Reader's Comment
Tuesday, July 7, 202010:54 PM
Guest
Dr Hoang - very good information. Thank you.
Saturday, April 18, 20201:46 AM
Super Administrator
Can I put this link to our website?

Yes.

Thursday, April 16, 20204:13 PM
Guest
Can I put this link to our website?
Monday, April 13, 20201:02 AM
Guest
Dr. Hoang - thank you for caring about us and sending this information. We will put into practice as much as we can as best we understand. You are the BEST and the one we trust in the cocophany of voices. God bless you and stay strong.
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